As with other NSAIDS, ibuprofen can cause stomach-related side-effects, so you should speak to your doctor if you tend to have problems such as heartburn or indigestion. Long-term use of NSAIDs, including ibuprofen, can also increase the risk of problems with your heart or circulation — especially if you have other risk factors for these conditions. Therefore you shouldn't take ibuprofen for long-term pain relief without seeing your doctor first, and you shouldn't take ibuprofen if you're also being prescribed another type of NSAID tablet.
Print this page. It can be used in low doses to reduce the risk of heart attack and stroke in high-risk patients. Prostaglandins are hormone-like chemicals in the body that contribute to inflammation, pain and fever by raising temperature and dilating blood vessels, which causes redness and swelling in the place they are released.
By reducing production of prostaglandins, NSAIDs help relieve the discomfort of fever and reduce inflammation and the associated pain.
While NSAIDs are effective in relieving pain, fever and inflammation, they can cause unwanted side effects. Gastrointestinal side effects such as indigestion , stomach upset including nausea or feeling sick or stomach pain are commonly caused by NSAIDs.
Use of NSAIDs can also cause ulcers and bleeding in the stomach and other parts of the gastrointestinal tract gut. NSAIDs with the exception of low-dose aspirin may also increase the risk of heart attack and stroke, even in healthy people. In general, using NSAIDs occasionally rather than every day, and at the lowest dose possible, reduces your chances of developing serious side effects.
Take paracetamol for mild to moderate pain and fever before a NSAID as it has fewer adverse effects, unless you have been advised otherwise by your health professional. A topical NSAID cream, gel or ointment may provide enough relief from muscle and joint pain and inflammation, or relieve discomfort caused by strains or sprains.
While NSAIDs can potentially cause many side effects — some of which may be serious or life-threatening — if prescribed under the right conditions and used as instructed, they can be of great benefit.
Risk factors include:. Tell your doctor or pharmacist if you have any of the risk factors above before buying or taking an NSAID. Alcohol can irritate the stomach lining. Regular or heavy drinking of alcohol while taking NSAIDs may increase the risk of gastrointestinal damage or bleeding. If you are taking another medicine, check with your health professional before taking a NSAID in case you might be at risk of unwanted effects.
Some over-the-counter medicines contain NSAIDs, for example, pain relief medicines and some cough, cold and flu medicines. Do not take more than one medicine containing an NSAID at the same time, unless your doctor recommends it.
If you are taking any over-the-counter NSAIDs, tell your doctor or pharmacist, particularly if you are due to undergo surgery or are starting a new medicine. This page has been produced in consultation with and approved by:.
Ankylosing spondylitis AS is a type of inflammatory arthritis that targets the joints of the spine. Most people take one pill by mouth daily. If you miss a dose, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take your next dose as usual.
Meloxicam tablets should be stored at room temperature and out of the reach of children. The price depends on the strength and whether you purchase brand name or generic pills. Combining meloxicam with other NSAIDs such as over-the-counter NSAIDs naproxen, acetaminophen, or ibuprofen increases the chance of developing gastrointestinal problems, like bleeding or ulcers. IV meloxicam may also cause GI problems, even though it is not taken by mouth.
Certain medications may put you at an increased risk of bleeding if taken with meloxicam because this prescription drug affects the function of platelets — a component of our blood that stops bleeding.
Blood thinners such as warfarin , antiplatelet agents such as aspirin , selective serotonin reuptake inhibitors SSRIs , and serotonin-norepinephrine reuptake inhibitors SNRIs should not be taken with meloxicam for this reason DailyMed, Drinking alcohol while taking meloxicam also increases your risk of bleeding problems FDA, Medications to treat high blood pressure may not work as well if taken with meloxicam.
Drugs that lower blood pressure antihypertensive drugs , like ACE inhibitors, angiotensin receptor blockers ARBs , or beta-blockers may be less effective if taken with meloxicam Fournier, ; Johnson, The FDA has issued a black box warning for meloxicam, which is a warning about serious or life-threatening complications that can arise from taking this medication. Black Box Warning: Meloxicam may increase the risk of heart attacks and strokes, especially in people with heart disease or other cardiovascular risk factors.
This risk may be higher if you use meloxicam long-term. Meloxicam should not be used to treat pain right before or after heart surgery, like a coronary artery bypass graft CABG procedure, as NSAIDs increase the risk of heart attack or stroke following these procedures Kulik, Meloxicam can also increase the risk of bleeding, ulceration, and holes perforations in the stomach or intestines FDA, NSAIDs such as meloxicam should also not be taken during the third trimester of pregnancy.
Last updated September 24, Written by Linnea Zielinski. Disclaimer If you have any medical questions or concerns, please talk to your healthcare provider. Vitals Black box warning: Meloxicam may increase the risk of heart attacks and strokes, especially in people with heart disease or other cardiovascular risk factors.
Meloxicam should not be used to treat pain right before or after heart surgery, like a coronary artery bypass graft CABG procedure.
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